RIR
A RIR is a regional internet registry, they generally service a continent or large regional body of land, and are typically used by very large ISPs or groups that have a specific need for direct IP assignment from the top. Generally you would go to a RIR when you need a large volume of IP addresses or have very specific routing policies that require several ASNs or other resources. RIRs also cost more than LIRs, however.